Effect of margin status on local recurrence after breast conservation and radiation therapy for ductal carcinoma in situ
Lectura recomendada por el Dr. Álvaro Vázquez. Fuente: Meta-Analysis J Clin Oncol. 2009 Apr 1;27(10):1615-20. doi: 10.1200/JCO.2008.17.5182. Epub 2009 Mar 2. Autores: Clive Dunne, John P Burke, Monica Morrow, Malcolm R Kell. Resumen:There is no consensus on what constitutes an adequate surgical margin in patients receiving breast-conserving surgery (BCS) and postoperative radiation therapy (RT) for ductal carcinoma in situ (DCIS). [...]
Molecular portraits of human breast tumours
Lectura recomendada por el Dr. Álvaro Vázquez. Fuente: Nature. 2000 Aug 17;406(6797):747-52. doi: 10.1038/35021093 Autores: C M Perou, T Sørlie, M B Eisen, M van de Rijn, S S Jeffrey, C A Rees, J R Pollack, D T Ross, H Johnsen, L A Akslen, O Fluge, A Pergamenschikov, C Williams, S X Zhu, P E Lønning, A L Børresen-Dale, P [...]
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
Lectura recomendada por el Dr. Álvaro Vázquez. Fuente: Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10869-74. doi: 10.1073/pnas.191367098 Autores: T Sørlie, C M Perou, R Tibshirani, T Aas, S Geisler, H Johnsen, T Hastie, M B Eisen, M van de Rijn, S S Jeffrey, T Thorsen, H Quist, J C Matese, P O Brown, D Botstein, P E Lønning, [...]
The molecular portraits of breast tumors are conserved across microarray platforms
Lectura recomendada por el Dr. Álvaro Vázquez. Fuente: BMC Genomics. 2006 Apr 27:7:96. doi: 10.1186/1471-2164-7-96 Autores: Zhiyuan Hu, Cheng Fan, Daniel S Oh, J S Marron, Xiaping He, Bahjat F Qaqish, Chad Livasy, Lisa A Carey, Evangeline Reynolds, Lynn Dressler, Andrew Nobel, Joel Parker, Matthew G Ewend, Lynda R Sawyer, Junyuan Wu, Yudong Liu, Rita Nanda, Maria Tretiakova, Alejandra Ruiz [...]
Deconstructing the molecular portraits of breast cancer
Lectura recomendada por el Dr. Álvaro Vázquez. Fuente: Mol Oncol. 2011 Feb;5(1):5-23. doi: 10.1016/j.molonc.2010.11.003. Epub 2010 Nov 24. Autores: Aleix Prat, Charles M Perou. Resumen: Breast cancer is a heterogeneous disease in terms of histology, therapeutic response, dissemination patterns to distant sites, and patient outcomes. Global gene expression analyses using high-throughput technologies have helped to explain much of this heterogeneity [...]
Dominantly inherited micro-satellite instable cancer – the four Lynch syndromes – an EHTG, PLSD position statement
Lectura recomendada por la Dra. Adriana Dela Valle. Conferencia 2017: “Cáncer Hereditario, de la genética molecular” Fuente: Hereditary Cancer in Clinical Practice (2023) 21:19. https://doi.org/10.1186/s13053-023-00263-3 Autores: Møller et al. Resumen: The recognition of dominantly inherited micro-satellite instable (MSI) cancers caused by pathogenic variants in one of the four mismatch repair (MMR) genes MSH2, MLH1, MSH6 and PMS2 has modifed our [...]